Scientists see several important uses for staging. For example, it can steer people more precisely to appropriate treatments.

The function of Tau protein belonging to microtubule-associated proteins (MAPs) is to stabilize the microtubule network within neuronal axons [26]. Tau protein is considered to play a central role in ...

Department of Neurology, Medical University of Lublin, Poland Department of Clinical Psychology and Neuropsychology, Faculty of Pedagogy and Psychology, Maria Curie-Skłodowska University, Lublin, ...

Protein Kinase A (PKA) is regulated spatially and temporally via scaffolding of its ... We identify Ser83 on the RIα linker-hinge region as an AKAP11-dependent phospho-residue that modulates RIα-Cα ...

Researchers have developed a highly accurate blood test for Alzheimer’s diagnosis using the biomarker phospho-tau217, offering earlier detection and lower costs. A study involving over 1,700 ...

Tau is a protein that is found in cells of the central nervous system and is involved in the assembly and stabilisation of neuronal microtubules – channels used to transport substances to ...

Autophagy is a process by which cellular material is degraded by lysosomes or vacuoles and recycled. Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and ...

Importantly, we also investigated whether reversing the activity of those altered genes would also reverse the motor alterations in flies and tau or beta-amyloid protein accumulation in cells ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

Tau is a protein that is found in cells of the central nervous system and is involved in the assembly and stabilisation of neuronal microtubules – channels used to transport substances to ...

What is known is that Pick's disease is characterized by the formation of so-called "Pick bodies." These occur when proteins normally found in nerve cells—known as called tau protein—clump together ...