Phase 1 trial of TGW101 in advanced solid tumors is enrolling to assess safety and pharmacokinetics and define the maximum ...

The trial will assess the therapy’s pharmacokinetics, pharmacodynamics and safety, as well as its impact on disease activity.

Getting therapeutic drugs past the blood-brain barrier has long been one of medicine's most difficult challenges, limiting ...

Pheast Therapeutics has treated the first subject in a multi-centre Phase I trial for the anti-cluster of differentiation 24 (CD24) macrophage checkpoint blocker PHST001, aimed at treating advanced ...

Denosumab works by specifically targeting the RANK ligand (RANKL), a critical protein in the lifecycle of osteoclasts, the cells that break down bone. This study enrolled a total of 204 healthy ...

Aurobindo Pharma's Bone Treatment Drug Shows Promise in Tests Aurobindo Pharma's subsidiary, CuraTeQ Biologics, has announced successful trial results for its new bone treatment medicine. The drug, ...

Critically ill patients, frequently characterized by an increased susceptibility to CAPA due to existing comorbidities, advanced age, dependence on invasive mechanical ventilation, renal replacement ...

Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences & Research Unit of Peptide Science, Chinese Academy of Medical Sciences, 2019RU066, Lanzhou ...

Thus, this study aims to systematically overview the pharmacological effects, pharmacokinetics and toxicity of paeoniflorin in diabetes. Plenty of evidences have verified that paeoniflorin improves ...

This potentially complex situation may alter drug pharmacokinetics to result in greater-than-usual intrapatient and interpatient drug exposure variability. These effects may call for individual dosage ...

Announced preclinical data demonstrating the bioequivalence of RT-114, a GLP-1/GLP-2 dual agonist (PG-102) delivered orally via the RaniPill® ...

But what really happens? How is your body processing the drugs and what happens if the dosage or timing is off? This is where the dual pharmacy specialties — pharmacokinetics (PK) and pharmacodynamics ...