When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens if the dosage ...
Developing new drugs to treat illnesses has typically been a slow and expensive process. However, a team of researchers at ...
Quantification and prediction of human fetal (-)-Δ 9-tetrahydrocannabinol/(±)-11-OH-Δ 9-tetrahydrocannabinol exposure during pregnancy to inform fetal cannabis ...
Background: Fentanyl, a short-acting synthetic opioid, has a pharmacokinetic profile suited to fast relief of brief episodic pain. Objective: To characterize the pharmacokinetic-pharmacodynamic ...
Background and Objective: Narcotic analgesics such as hydromorphone undergo an extensive first-pass effect resulting in a low systemic bioavailability following oral administration. Alternative ...
We have previously demonstrated an apparent decrease in renal tubular secretion and an increase in plasma half-life for furosemide (F) in VLBW infants. To pharmacokinetically characterize ...
On Tuesday, Adial Pharmaceuticals Inc (NASDAQ:ADIL) announced the progression to the second cohort in the pharmacokinetics study of AD04. AD04 is the company’s lead investigational genetically ...
Trial achieved key objectives for safety, tolerability, pharmacokinetics and pharmacodynamicsClinical data from this trial, together with ...
Innovative organ-on-chip specialist Dynamic42 and ESQlabs, experts in digital life sciences solutions, have successfully ...
A groundbreaking Phase 1 study suggests that once-yearly intramuscular lenacapavir could be a promising option for HIV PrEP.
Merck has shared data from the pivotal Phase 3 trial evaluating the subcutaneous administration of pembrolizumab together ...
First-in-human study evaluating a novel long-acting injectable antiretroviral therapy provides promising early results on its ...