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We first investigated the effect of the mitotic cyclin/Cdk1 complex Cyclin B/Cdk1—functional homolog in mammalian cells of the budding yeast Clb2/Cdk1—on yeast metabolic enzymes of, or related to, the ...

For example, activation of GLUT3 and LNC00842 transcription enhances aerobic glycolysis in tumor cells, while downregulation of YY1 by MZF1 inhibits the transcription of its downstream glycolytic ...

Mechanistically, Acod1 suppressed osteoclast differentiation by inhibiting succinate dehydrogenase-dependent production of reactive oxygen species and Hif1α-mediated induction of aerobic glycolysis.

1Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, China. 2Shandong Engineering Research Center of ...

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