By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...

Candidate genetic variants included in a genetic risk algorithm may not meet standards of reasonable clinical efficacy in identifying opioid use disorder risk, according to a study published in JAMA ...

Researchers have uncovered a way to manipulate DNA at the atomic level using electric field gradients to control nitrogen ...

NLR (nucleotide-binding domain, leucine-rich repeat containing) family proteins structurally and functionally resemble APAF1 (apoptotic-protease activating factor 1), an apoptotic mediator ...

Scientists have successfully engineered the most complicated human cell lines ever indicating that our genomes are more tolerant to significant structural alte ...

This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

AI models are able to design molecules that don’t even exist in nature. Some have proven effective as snake antivenom.

A team from the University of Geneva and Bayer AG present their findings on the on-off retention of oligonucleotides and the ...

The most advanced engineering of human cell lines to date has been accomplished by scientists, demonstrating that genomes are more robust against significant structural changes than previously ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.