We now have to change the way we classify, diagnose and treat neuropathic pain from an etiology-based to a mechanism-based approach. In clinical practice, the diagnostic work-up should aim at ...

Neuropathic pain syndromes remain a major therapeutic ... If these possibilities are correct, we could develop a new generation of mechanism-based drugs that can mute the roar of pain effectively.

Phantom limb pain following amputation correlates with primary somatosensory cortex (S1) reorganization. Wrigley et al. hypothesized that a similar mechanism underlies persistent neuropathic pain ...

Neuropathic pain syndrome is a challenge to treat and ... including a fundamental mechanism-based approach, a clinical mechanism-based approach and an evidence-based approach.

Researchers are approaching a new level of understanding for the neuropathic pain-relief mechanisms of gabapentin. And the momentum generated by such a discovery may bring better tidings for the ...

Neuropathic pain can occur after severe injuries and ... Algiax's candidate offers a new potential mechanism of action for pain relief, and is thought to work by correcting excessive activation ...

tells The Scientist that “we identified a new mechanism of chronic pain.” Specifically, he explains that the study identifies a mechanism that leads to neuropathic pain—a type of chronic pain caused ...

MIRA Pharmaceuticals, Inc. (NASDAQ:MIRA), a clinical-stage pharmaceutical company developing breakthrough therapeutics for neurologic and neuropsychiatric disorders, today announced the enrollment of ...

The researchers discovered that this kind of therapy can reduce neuropathic pain, promote urinary function, and decrease neuroinflammation. They also discovered a mechanism through which ...

This unique mechanism is believed to contribute to ... has granted Fast Track designation to AV-101 for the treatment of ...

"Ketamir-2's unique mechanism and pharmacological profile make it a highly promising candidate for neuropathic pain. If successful, it could represent a safer, non-addictive alternative to opioids ...

Vertex is also exploring the potential of suzetrigine in treating peripheral neuropathic pain ... The therapy’s mechanism ...