Retroviruses are negative single-stranded RNA viruses in which tRNA serves as a primer for the ... of viral supernatant by transient transfection as well as assay for replication competent retrovirus.

Our findings indicate that negative results obtained with subcloned DNA must be interpreted with caution and should motivate, if feasible, the use of linear, vector-free expression constructs in C.

ViroCell Biologics ("ViroCell" or the "Company"), a specialist viral vector Contract Development and Manufacturing ...