Nuclear magnetic resonance (NMR) spectroscopy is a technique that detects the chemical environment of atomic nuclei by the absorption of radio-frequency electromagnetic radiation when in the ...
Insoluble α-synuclein (αSyn) filaments in brain tissue are a hallmark of Parkinson’s disease (PD) and Multiple system atrophy (MSA), and for structural studies, they have for decades been extracted ...
Department of Chemical and Petroleum Engineering, Center for Environmentally Beneficial Catalysis, and Wonderful Institute for Sustainable Engineering, University of Kansas, Lawrence, Kansas 66045, ...
Several studies have shown how α-synuclein, amyloid-β, tau and other amyloidogenic proteins can act as nucleating particles and thereby share properties with misfolded forms, or strains, of the prion ...
In a paper published last year, an international team of scientists describes how the two proteins work together to help harmful alpha-synuclein protein clumps get into brain cells. "Now that we know ...
Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.
Biophysical studies of a 21-residue phosphorylated PRLR fragment using isothermal titration calorimetry (ITC) and NMR spectroscopy show an interaction with a kinetic phase on the minute time scale. In ...
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