Distribution of non-P42 MOG-IgG in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) at onset. Credit: Journal of Neurology, Neurosurgery & Psychiatry (2024). DOI: 10.1136 ...

A new study has identified the protein hnRNP A1 as a key player in the production and maintenance of myelin, the fatty sheath ...

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and ...

The molecular mechanisms underlying myelin sheath destruction in multiple sclerosis lesions remain unresolved. With immunogold–labeled peptides of myelin antigens and high–resolution ...

have identified a distinct histone tag in adult oligodendrocyte progenitor cells (OPCs) that may pave the way for innovative therapies targeting myelin repair, a critical target for several ...

Study uncovers how the protein hnRNP A1 may impact myelin stability, offering new clues in schizophrenia development.

The researchers began to suspect that the APOE4 variant hindered cholesterol transport across oligodendrocyte membranes. Imagining that oligodendrocytes function like myelin printers, the emerging ...