This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

Beyond its role in the initiation of digestion, the oral microbiome appears to be key to maintaining both oral and systemic ...

Gut microbiota composition and sex hormones influence the immune response to methicillin-resistant Staphylococcus aureus gastrointestinal colonization in mice.

IgM is the first antibody to be produced in a humoral immune response and plays an important role in the primary stages of immunity. Here we describe a mouse Fc receptor, designated Fcα/μR ...

Blood was drawn in 5-ml EDTA vials, and plasma was aliquoted and stored for plasma antibody-based HIV-1 neutralization assays, viral RNA isolation, and viral load determinations. The deep sequencing ...

CD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing ...

Changes in or damage to the cellulosity or local environment of the intestinal tract can cause various diseases. Single-cell RNA sequencing (scRNA-seq) is a powerful tool for profiling and analyzing ...

Drug discovery efforts have expanded beyond the traditional approaches of small molecules and antibodies to include cells.

Analyses of single-cell transcriptomic data from patients with VEXAS syndrome combined with xenotransplantation experiments in a mouse model ... a humanized monoclonal antibody that targets ...

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Immunizing mice with an edited Lyme disease-causing bacterial protein effectively protected them against the disease.