A new study reveals that microRNAs—tiny regulators of gene expression—play a crucial role in shaping Purkinje cells, rare brain neurons linked to movement and neurodevelopmental disorders.

Psychiatric disorders challenge us deeply. At the University of Arizona, researchers dissect their molecular roots, focusing ...

This review highlights the miRNA-mRNA target networks essential for chondrocyte differentiation ... Moreover, many miRNAs exhibit preferential expression in specific growth plate zones (Figure 2), ...

Colorectal cancer is a serious but preventable disease if detected early. Advances in diagnostics, such as biomarker analysis ...

Specifically, there is increasing evidence underlining those miRNAs can influence the way that cells respond to ionizing radiation, making them more radiosensitive or radioresistant through several ...

Researchers have validated a specific cluster of microRNAs (miRNAs) as reliable biomarkers for detecting malignant testicular ...

Intriguingly, the miRNA miR-8055, partially investigated ... challenges due to their low expression levels, tissue-specific ...

RALY acts as a key regulatory component in the Drosha complex, and promotes the post-transcriptional processing of a specific subset of miRNAs (miR-483, miR-676 and miR-877). These miRNAs ...

RNA-based therapeutics are gaining traction due to advancements in delivery technologies, despite historical challenges with ...

Malignant testicular germ cell tumors are the most common cancers diagnosed in males ages 15 to 39 in the U.S., though ...

bMIND is a Bayesian deconvolution method to integrate bulk and scRNA-seq data. With a prior derived from scRNA-seq data, we estimate cell-type-specific (CTS) expression from bulk tissue expression via ...