These Dp1Tyb mice also needed louder sounds to initiate a response in their brains, suggesting they had hearing loss. Using gene mapping, the team narrowed down that a gene called Dyrk1a, found on ...

A century after Down syndrome was first described ... induced translocations involving these mouse chromosomes, producing mice that are trisomic for regions suspected to play a role in DS.

Down syndrome, or trisomy 21, is caused by the presence of a third copy of the 21st chromosome. Affected individuals have ...

Polycystic ovary syndrome—a hormonal disorder that can manifest as ... A study published this week (February 3) in Cell Metabolism suggests that mice can pass down PCOS-like symptoms for at least ...

There has been no definite link to external stimuli resulting in increased seizure activity, though the association of the syndrome in these mice with movement to different rooms within the ...