We found that pro-IL-1β is the main and only target of starvation-induced catabolism. Surprisingly, mTOR inhibition with rapamycin, a known inducer of autophagy ... Cells were lysed in M-PER™ ...

Presenter: Amy Paller, M.S., M.D., Walter J. Hamlin Professor and Chair of Dermatology, Professor of Pediatrics, and ...

This study determined whether pharmacological inhibition of the mammalian target of rapamycin (mTOR), a key inhibitor of autophagy, has disease-modifying activity in experimental osteoarthritis.

Upon close of merger and $78.9mm concurrent private placement from a syndicate of leading healthcare-dedicated investors, completed ...

There may be pathways that, although deregulated relatively rarely, are key to driving specific tumours. Mammalian target of rapamycin (mTOR) inhibition can lead to proliferative arrest and even ...

These two amino acids, methionine and leucine, are known activators of a signaling molecule called mTOR (mammalian target of rapamycin). Leptin-sensitive animals showed no such dysregulation.

These two amino acids, methionine and leucine, are known activators of a signaling molecule called mTOR (short for “mammalian target of rapamycin”). Leptin-sensitive animals showed no such ...

Pathways related to extracellular matrix, mammalian target of rapamycin signalling, splicing of introns and exons and the ribosome complex are proposed to be involved in abnormal lung ageing in COPD.

弥漫大 B 细胞淋巴瘤（DLBCL）治疗面临困境，常规化疗对约三分之一患者疗效不佳。研究人员开展 TAFA 联合节拍化疗（mCHEMO）治疗 DLBCL 的研究。结果显示，二者协同抑制肿瘤细胞活性，体内外实验均有效，有望用于临床试验。

It can be caused by dysregulation of the phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) pathway. In December 2023, the company entered a partnership with Ligand ...