Over the past few years, however, data and drugs associated with the hypothesis have been mired in various controversies relating to data integrity, regulatory approval, and drug safety.

The errant growth of this protein is responsible for triggering an increase in tangled threads of another protein called tau and the development of Alzheimer’s disease — at least according to the ...

This reduction in the number of contacts likely weakens the binding strength. This hypothesis is further supported by the observation that the two molecular partners are farther apart in the mutated ...