Here, the authors establish an EV-A71 infected skin organoid model to study the virus infection pathogenesis and drug screening. The authors identify an autophagy-associated protein as drug target ...

Two pathways are conceivable: Either the ligand binds preferentially to a rare conformation with higher affinity (“conformational selection”) or the ligand first binds to the dominant conformation and ...

Consumers who have and spend disposable income on non-essential items produce induced consumption. These consumers have money to spend or invest, even after all basic needs are met, and all ...

Alcoholic insanity is an outdated term to describe alcohol-induced psychosis. This is a rare condition in which alcohol use disorder, acute alcohol intoxication, and alcohol withdrawal can cause ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, 2318 Yuhangtang Road, Hangzhou 311121, PR China Department of Chemistry, and the ...

BRIDGETOWN, Barbados (CMC) — Caribbean Community (Caricom) foreign ministers have been told that the United States (US) Secretary of State, Marco Rubio, is expected to travel to the Caribbean ...

Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Haihe Laboratory of Sustainable Chemical Transformations, College of Chemistry, Nankai University, Tianjin 300071, P. R.

The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...

However, we know much less about the repressors that stop cells burning fat when there is plenty of food available. To find out more, Sommars et al. studied the repressor BCL6 in mouse liver cells.