Figure 2. Cardiac hypertrophy mediated by MyD88-dependent and independent TLRs signaling pathways. Numerous specific protein serine/threonine kinases participate in TLR signaling, such as IL-1 ...

IL-9 was co-localised with the key Th9 transcription factors interferon regulatory factor 4 and PU.1. Systemically, IL-9 was abundantly produced by activated peripheral blood lymphocytes, whereas its ...

IL-1R, Interleukin-1 receptor; IL-1Ra, Interleukin-1 receptor antagonist; IRAK4, Interleukin-1 receptor associated kinase 4; IL-10, Interleukin-10; IL-18, Interleukin-18; IL-18BP, Interleukin-18 ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

It affects 1-2% of the population and is thought to be caused by misguided T cell attacks on the skin. IL-36 receptor is crucial for host defense and tissue repair. Here, the authors describe ...

Glucagon-like peptide 1 receptor agonist use was not associated with an increased risk for thyroid cancer compared with use of dipeptidyl peptidase-4 inhibitors. HealthDay News — Glucagon-like peptide ...

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A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage ...

Locked Bag 1, Newcastle, NSW 2305, Australia; joerg.mattes{at}newcastle.edu.au Background Asthma exacerbations represent a significant disease burden and are commonly caused by rhinovirus (RV), which ...

BTIG analysts upheld their Buy rating and $15.00 price target for Coya Therapeutics (NASDAQ:COYA), following recent clinical trial data. The stock, currently trading at $7.11, has shown strong ...

Emiliano Medei, a researcher at IDOR and UFRJ, interleukin-1 beta (IL-1β)—a molecule of the immune system involved in ...