The HMGB1 primer sequences were: sense 5′-CAC CGT GGG ACT ATT AGG AT-3′ and antisense ... used to detect nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) activity using an NF-κB ...

Cardiac hypertrophy constitutes the primary pathological basis for heart failure and exerts a considerable influence on morbidity and mortality. Deubiquitinating enzymes are crucial regulators of ...

HMGB1 that belongs to the High Mobility Group-box superfamily, is a nonhistone chromatin associated transcription factor. It is present in the nucleus of eukaryotes and can be actively secreted or ...

This work presents important findings regarding the interaction of the monkeypox virus (MPXV) attachment H3 protein with the cellular receptor heparan sulfate and the use of this information to ...

HMGB1 lacks signal peptide and utilizes diverse non-canonical secretion mechanisms ... Proteins in the HMGA family contain an AT-hook, which is a DNA-binding motif with a preference for A/T rich ...