To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where ...

In a preprint posted on bioRxiv, Profluent introduces a new method which now incorporates structural and functional context to protein language models for conditioned design. The approach, termed ...

image: (a) Protein sequence-structure co-design with PocketGen; (b) Dual-layer graph Transformer encoder; (c) Pre-trained protein language model for sequence prediction and efficient fine-tuning.

De novo protein design. In 2024, David Baker won the Nobel Prize in Chemistry for computational protein design and the prize was shared with Demis Hassabis, and John Jumper for protein structure ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought.

Traditionally, high-protein food and drink makers have leant heavily on whey, a byproduct of the cheese and yogurt-making process. But as consumer demand evolves, innovators are exploring new ...

Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

Inverse protein folding is important but difficult because small changes in protein sequences can cause unpredictable effects on the protein's structure For medicines to work properly, proteins ...