Inhibition of EV biogenesis with GW4869 prevented FtH release and restored LIP accumulation, lipid peroxidation, and ferroptosis sensitivity in COV318 and PEO4 cells. Discussion: Overall, our results ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent reactive ...

In contrast, the transcription levels of ferroptosis regulatory factors—such as solute carrier family 7member 11 (SLC7A11), ferritin light chain (FTL), ferritin heavy chain 1 (FTH1), NAD(P)H quinone ...

Ferritin is a crucial protein that aids in storing iron in the body and plays a significant role in assuring iron equilibrium and ensuring efficient cell functions with the provision of necessary ...

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Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.