M1 macrophages, with higher ferritin expression, are more resistant to ferroptosis than M2 macrophages. Pathogen ingestion can also trigger macrophage ferroptosis, releasing harmful lipid ...

M1 macrophages, with higher ferritin expression, are more resistant to ferroptosis than M2 macrophages. Pathogen ingestion can also trigger macrophage ferroptosis, releasing harmful lipid ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

已有研究表明，miR-34a-5p 参与细胞铁死亡（ferroptosis）的调控。此次研究旨在探索 miR-34a-5p 在 ... 而 SIRT1、谷胱甘肽过氧化物酶 4（GPX4）、铁蛋白（Ferritin）和谷胱甘肽（GSH）的表达水平则上调。miR-34a-5p 可能通过直接靶向 SIRT1，调控参与神经元铁死亡的 Wnt/β-catenin ...

Hepatocellular carcinoma (HCC) represents the most prevalent form of liver cancer. Despite notable advancements in therapeutic strategies, HCC continues to pose significant public health challenges ...