This article makes a valuable contribution to the field by uncovering a molecular mechanism for miRNA intracellular retention, mediated by the interaction of PCBP2, SYNCRIP, and specific miRNA motifs.

A study by the Center for Redox Processes in Biomedicine (Redoxoma) led by Marilene Demasi from the Butantan Institute (São ...

A study by the Center for Redox Processes in Biomedicine ( Redoxoma ) led by Marilene Demasi from the Butantan Institute (São Paulo, Brazil ...

Despite having identical genetic instructions, female honey bee larvae can develop into either long-lived reproductive queens ...

Researchers discovered that genetic conflict between paternal and maternal genes determines whether honey bee larvae become ...

Cracking the genome's switchboard: How AI helps decode gene regulation by Aliyah Kovner, Lawrence Berkeley National Laboratory edited by Lisa Lock, reviewed by Robert Egan Editors' notes ...

How protein kinase A (PKA) is reset to a basal state following 3′5′-cyclic adenosine monophosphate (cAMP)-mediated activation is unknown. Here we describe the mechanism of cAMP-PKA type I signal ...

Manipulating Gene Expression to Treat Disease Several of our scientists study gene regulation in specific cancers, including cancers of the blood, lung, pancreas and prostate. They seek treatment ...

The role of genetic variation at the 3' end of the apolipoprotein B gene locus in the development of coronary heart disease and the regulation of the serum levels of various lipoproteins was studied ...

The gene therapy, called P-KLKB1-101, edited KLKB1 to therapeutic levels in mice with just a single dose, the company said in the release. At the minimally effective dose of 0.125 milligrams per ...