A new study has unveiled a genetic breakthrough that could transform the flavor profile of apples, even in the face of ...

Atherosclerotic cardiovascular disease is a major health concern worldwide and requires effective preventive measures. Lp(a) (lipoprotein [a]) has recently garnered attention as an independent risk ...

Natural product synthesis aims to prepare a complex target ... Here, the authors dissect the mechanism of a promiscuous flavoenzyme from the biosynthesis of cyclodipeptide natural products ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

The most common method for creating an amide bond is the use of carbodiimide condensing agents such as dicyclohexylcarbodiimide and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride. The ...

A recent breakthrough by researchers from Shinshu University, Japan, is changing this landscape. The team has successfully achieved the first total synthesis of inaoside A, a natural compound found in ...

In this Review, we summarise common mechanisms driving acute and long-term side-effects and discuss monitoring strategies for radiotherapy survivors. We explore ways to mitigate toxic effects through ...

"Although the α-D-ribofuranoside structure is frequently found in natural products, there have been fewer reports of the synthesis of α-D-ribofuranosides than of the β-anomers. Thus, the ...

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

The international team describes their results and the underlying molecular mechanism in Cell Metabolism. Ergothioneine is a natural compound found in certain fungi such as oyster or shiitake ...

Adrenocorticotropic hormone (ACTH) released by the pituitary gland evokes glucocorticoid synthesis by adrenal cortex. CRF and ACTH production is inhibited by glucocorticoid feedback. Norepinephrine is ...

Phostdoctoral Research Base, School of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang, Henan Province 453003, China Postdoctoral Research Station, School of ...