The Grignard reaction represents one of the most powerful carbon-carbon bond forming reactions and is the subject of continual study. Here, the authors report a halide effect on the ...

While performing a high-throughput screen (HTS) that identified the hits that led to the discovery of TNG908 and TNG462, we embarked on a structure-based design effort to switch the mechanism of ...

INSA Rouen Normandie, Univ Rouen Normandie, CNRS, Normandie Univ, COBRA UMR 6014, F-76000 Rouen, France ...

Agglomerates were prevented by stirring at intervals, and the TMP hydrolysis treatment was quickly followed by adjusting the reaction solution to 1 L with 6 mol/L phosphate buffer ... Reactive oxygen ...

The rumbling was felt up and down the New England coast, and while most reactions were of the “Did you feel that??” variety, there were also plenty of clever takes from Greater Boston ...

Allergies are an immune system reaction to substances called allergens. The cause a range of symptoms from a stuffy nose to itchy eyes to difficulty breathing. How long allergies last varies based on ...

As such, social media reactions have ranged from despair, apathy, laughter and everywhere in between. Here are some of the best responses. No matter how bad things may seem for the Lions with ...

In this Review, we summarise common mechanisms driving acute and long-term side-effects and discuss monitoring ... Radiotherapy can cause both acute and late toxic effects (figure 2). The acute (early ...

A research team has made significant discoveries regarding the complex reaction mechanisms of carbon dioxide (CO₂) in supercritical water. These findings are crucial for understanding the ...

It will form the basis to develop theories to provide further insight into the mechanism of reaction acceleration by applied mechanical forces," said the study's first author, Associate Professor ...