Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how ...

The scientist who discovered hybridization and the "other" double helix describes what it meant to biology. By Alexander Rich Fifty-two years ago I was venturing to the basement of Cal Tech chemistry ...

ADAR1 converts adenosine to inosine in double-stranded RNA, a key process for preventing unwarranted immune responses, yet ...

ADAR1 converts adenosine to inosine in double-stranded RNA, a process essential for preventing unwarranted immune responses, yet the molecular basis of this editing had remained unclear.

Specifically, one strand of a double-stranded siRNA molecule can be incorporated into a complex called RISC. This RNA-containing complex can then inhibit transcription of an mRNA molecule that has ...

which can make the RNA catalytically active," explains Boekhoven. Double-stranded RNA therefore has two advantages: it has an ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases (Image: Wikimedia Commons, CC SA 3.0) Transfer RNA (tRNA) molecules are responsible for delivering ...

In a further important step, they were now able to combine several of these siRNA molecules into so-called efficient double-stranded RNA molecules (edsRNAs), which are particularly suitable for use in ...

Discover how a structural breakthrough in the chikungunya virus is opening new avenues for antiviral drug development and ...

although genetic siRNA is more stable being double-stranded, but less active. All current approvals are either antisense or siRNA, Aptamers: using RNA molecules similarly to small molecules to ...

ADARs are a family of enzymes that catalyze the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) substrates. Mammals have three ADAR genes: ADAR1, ADAR2, and ADAR3. ADAR1 ...