Reviewer #1 (Public review): Summary: In this manuscript the authors present a novel CRISPR/Cas9-based genetic tool for the dopamine receptor dop1R2. Based on the known function of the receptor in ...

Summary: Dopamine receptors in the ventral hippocampus play a critical role in balancing approach and avoidance behaviors, expanding understanding beyond dopamine’s known functions in reward and ...

The team characterized the function of D1 and D2 dopamine receptors in the ventral hippocampus of mice, a region involved in the regulation of emotions and stress responses. Their work expands the ...

Dopamine also plays a major role in how you experience pleasure and reward, Verhulst says, which your brain and body craves. More On Joy And Mental Health 10 Benefits Of Walking, According To Experts ...

And while dopamine has been well studied in the context of positive reinforcement, i.e., the receipt of something good, dopamine neurons also respond to aversive stimuli and associated cues, they ...

When dopamine binds to D1 receptors, it helps enhance signal processing in areas of the brain crucial for focus and attention. On the other hand, D2 receptors are more involved in modulating the ...

A new study has uncovered why stimulant medications like Ritalin don’t help everyone with attention deficit hyperactivity disorder (ADHD). While nearly 16 million adults in the U.S. have been ...

The dopamine D1 receptor (D1R) has fundamental roles in voluntary movement and memory and is a validated drug target for neurodegenerative and neuropsychiatric disorders. However, previously developed ...

A dopamenu is useful not only for people with ADHD, Tivers added, but also a host of other conditions, such as depression or seasonal affective disorder (SAD), in which low dopamine is a factor.

Dopamine is a key neurotransmitter known to modulate motivation and reinforcement learning. While the role of dopamine in these reward-related processes is well-established, the cellular and ...