Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

The ability to analyze gene expression at the single-cell level—known as single-cell RNA sequencing (scRNA-seq)—has ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

Gene expression analysis plays a critical role in candidate preclinical safety and toxicity screenings as well as in monitoring therapeutic efficacy and off-target effects to ensure biologics are ...

“Hormones and DNA are two powerful factors that can push a gene into being switch-like,” Aqil says. “Typically, lots of small ...

To enhance productivity in research laboratories conducting genomic studies, automation techniques along with rapid workflows are encouraged. Here, we discuss gene expression analysis by ...

Gene expression analysis using qPCR quantification of RNA transcripts expressed by cells or viruses plays an important role in the discovery and development of novel biotherapeutics. While widely used ...

The Perturb-Multi method combines imaging and sequencing to study gene function in intact tissue. By analyzing liver tissue ...

Gene expression in the human brain: cell types become more specialized, not just more numerous Date: January 2, 2025 Source: University of California - Santa Barbara ...

The study aims to identify patterns of changes in gene activity during insect development that undergo complete metamorphosis from egg to larva, pupa, and adult. The results were published in the ...