Scientists at Sanford Burnham Prebys and collaborators across the country published findings March 5, 2025, in Nature ...

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...

In total, just 68 nucleotides were needed for DNA hydrogel formation—markedly less than the hexapodna-based DNA hydrogel composed of 12 different 40-base long ODNs," explains Prof. Nishikawa.

Connecting DNA "Sometimes, a cell needs to be quick in changing which genes should be expressed and which ones should be turned off, for example in response to food, alcohol or heat. To turn genes ...

Two new studies uncover how DNA folding controls sperm cell development. Researchers identified proteins that rearrange ...

Thus, the 3’-OH is important for step 2 chemistry even though it is not itself chemically transformed during DNA-adenylate formation. To delineate the ligase-DNA interface, we footprinted the ligase ...

used nanoengineered DNA strands in a three-point star shape to isolate and examine the different factors controlling crystalline supramolecular network formation. In the process, they discovered a ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...

This stalled meiotic progression coincided with the activation of a DNA damage checkpoint, triggered by double-strand break formation, leading to defects like chromosome fraying and fragmentation.

In total, just 68 nucleotides were needed for DNA hydrogel formation -- markedly lesser than the hexapodna-based DNA hydrogel composed of twelve different 40-base long ODNs,"explains Prof.