“This is really an exciting paper . . . a true engineering feat. It elegantly increases the number of DNA and RNA building blocks and dramatically expands the information density of nucleic acids,” ...

It can also make sense of existing DNA, including hard-to-interpret ‘non-coding’ gene variants that are linked to disease. ‘ChatGPT for CRISPR’ creates new gene-editing tools Evo 2 ...

A contaminating human DNA sequence present in a fish assembly ... Chain and nets are also valuable for spotting unflagged protein coding and noncoding pseudogenes, including ribosomal ones.

Through combinatorial color coding and iterative hybridization and imaging cycles, researchers can identify thousands of RNA species with this strategy. In single-cell RNA sequencing (scRNA-seq), ...

DNA is the molecule that holds the instructions for all living things. DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of ...

Did you know that many of us have up to 4% neanderthal DNA? And that 100% of your DNA may come from outer space? No joke. The biochemistry that defined the coding system of your D ...

The researchers studied resistance variants found in the non-coding genome, which makes up 98% of DNA and does not contain genes. Previous attempts to identify resistance mechanisms to ...

LncRNAs and circRNAs are key regulators of gene expression, influencing disease mechanisms and offering potential as ...

In 1953, James Watson and Francis Crick proposed the double-helix model of DNA based on X-ray crystallography data collected by Rosalind Franklin and Maurice Wilkins. This discovery laid the ...

Swiss start-up Haya Therapeutics has formed a partnership with Eli Lilly – worth up to $1 billion – to look for new therapies for obesity in non-coding DNA. The biotech focuses on trawling the ...