However, most animal cells have complex morphologies because the membrane adheres strongly to the cytoskeleton. In animal cells, movement of membrane into an endocytic vesicle or lamellipodium ...

Surprisingly, some T-cell functions were normal ... indicates that HEM1 has an integral role in the rearrangement of the cytoskeleton of adaptive immune cells. The defect in actin polymerization ...

Now the team has found that the gene's activation of actin cytoskeleton also enhances immune function. "Our research shows ...

The research focuses on cells’ “feet,” which are small bundles of molecules that help cells move. Scientists are exploring ...

Our group uses a wide range of biophysical, biochemical, cell biological, and genetic approaches to uncover the general principles underlying regulation of the actin cytoskeleton, and to reveal how ...

Approximately 15% of the proteins produced in our bodies are destined for the surface of our cells. Remarkably, these surface proteins ... In our lab, we aim to elucidate the interplay of clathrin ...