Shock!! Ninety-eight-year-old Eli the priest hears they lost the war; his sons are killed; the Ark of God is taken (1 Sam. 4:17,22); God's judgment (2:27-34); God deals with the Philistines (5:1-12; 6 ...

Generative Phosphoproteomics AP3 platform designed to enable streamlined, rational drug discovery, with proprietary, proteome-wide SAR delivering desirable pathway effects R&D event highlighted ...

Furthermore, PNKP is involved in poly (ADP-ribose) polymerase 1 (PARP1)-dependent replication gap filling as part of a backup pathway in the absence of OFs ligation. Altogether, our data suggest that ...

CEP135 associates with SAS6 to link it to CPAP. Checkpoint kinase 1 (CHK1) phosphorylates and inhibits cell division cycle 25 (CDC25) A/C, which is responsible for dephosphorylating and activating ...

4. Expansion opportunities: Success in endometrial cancer could pave the way for ACR-368’s use in other cancer types where the CHK1/2 pathway is implicated. 5. Combination potential: Acrivon’s ...

Cantor Fitzgerald also highlighted inquiries regarding the potential for an accelerated approval pathway based on the ... ACR-368, specifically targeting CHK1/2i, and ACR-2316, aimed at WEE1 ...

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Finally, we continue to expand the actionable capabilities of our Generative Phosphoproteomics AP3 platform to enable us to optimize therapeutic compounds for desired pathway effects, which drives our ...