New research in eGastroenterology identifies the unfolded protein response (UPR) as a crucial mechanism in maintaining ...

Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

A newly discovered bat coronavirus uses the same cell-surface protein to gain entry into human cells as the SARS-CoV-2 virus ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

The new discovery raises the possibility that it could some day spread to humans. Read more at straitstimes.com.

Tuft cells are found in the lining of the intestines and are implicated in monitoring the immune system. They survey the gut's luminal environment and signal other cells if they detect potential ...

The intestine is continually exposed to challenges from the diet, commensal microbiota or infectious microbes. As a result, the gut is also host to a complex network of immune cells that work together ...

Once such epitopes are found, specialized cells from the immune system, called lymphocytes, destroy the foreign proteins. Epitopes (Fig. 4) usually contain between eight and 11 amino acids. Normally ...

Peyer's patches as immune hubs: Peyer’s patches in the small intestine are crucial for inducing T-cells in response to dietary antigens, forming a first line of defense against tumor formation .

Micro- and nanoscale plastic particles in soil and water can significantly increase how much toxic chemicals plants and human ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...