This expanded capability enables the expression, purification and stabilization of challenging membrane proteins, which are often key targets in therapeutic development. Using cell-free protein ...

"Large-scale protein-protein interactions within the cell membrane are an area that the community is just starting to embrace and appreciate the importance of, so we are well positioned to ...

Nuclera, announced the addition of a new membrane protein workflow to its system. This expanded capability enables the expression, purification and stabilization of challenging membrane proteins, ...

A new proteomic analysis, co-localization of the aggregates with the ER membrane Sec61beta protein, expression of the aggregate-prone protein in the nucleus does not result in accumulation of ...

ensuring pharmacological stability by mimicking the cell’s native environment. This stability enables the application of hit identification approaches such as fragment-based screening (FBS). The ...

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate ...

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