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揭秘膀胱癌中 p53 突变奥秘,构建创新小鼠模型助力免疫抗癌研究
为解决膀胱癌研究中机制不明、模型缺乏等问题,研究人员开展关于膀胱癌中 p53 突变及相关机制的研究。结果发现 p53 突变 LOH 等关键机制并建立新小鼠模型。该研究为膀胱癌研究提供新思路与工具,推荐科研读者阅读。
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