发现1例新型COL1A1纯合错义变异（c.4340T>G）及3例COL1A2/COL1A1杂合变异，拓展了COL1相关重叠疾病的表型谱，为胶原蛋白病诊断提供新依据。 胶原蛋白是人体重要的结构蛋白，其中I型胶原由COL1A1和COL1A2基因编码，构成骨骼、皮肤等组织的核心支架。

发育期牙髓的ECM特征 免疫荧光显示，年轻恒牙（发育期）中FN、LAMA4和COL1A2表达量显著高于成熟牙髓（图2A-F）。 这种ECM成分的时空特异性分布提示，发育期牙髓可能存在独特的"ECM代码"指导血管网络构建。 PDGFRβ+DPSCs的ECM编程能力 ...

Complications of Pregnancy and Delivery Because of the pregnancy-associated risks, and the potential for transmission, the optimal time to determine genetic risk is before pregnancy, especially if ...

Elizabeth J. Lawrence, RNC, MSN, NNP Disclosures Adv Neonatal Care. 2005;5 (6):301-314.

华盈生物提供的定量蛋白组学技术 鉴定了1409种hUCMSC-EVs蛋白，这些蛋白富集到很多组织重建的通路上。特别是含量高的很多蛋白参与超高分子纤维组成（COL1A2, VIM, ANXA2, TF, COL1A1, FN1），及细胞骨架组成（KRT1, COL6A3, COL1A1, KRT86, KRT10)，这些都与纤维化直接相关。

Meanwhile, cells in cluster 1 and 6 were considered as intermediate cells (ICs) during 2C-induced reprogramming of CMs to RCCs, because of expression of ACTA2, a marker gene reported to express in CM ...

Aligning AMELX and AMELY sequences from Bison bison, Bos taurus and Homo sapiens (Figure S1); sequence alignment of B. taurus and Bison bison for COL1A2, COL1A2, ameloblastin, enamelin, ...

ABSTRACT The authors present a case of Osteogenesis Imperfecta, emphasizing the clinical and epidemiological characteristics, forms of classification and treatment of the disease. This is an important ...