本研究针对HPV16与沙眼衣原体共感染促进宫颈癌的分子机制不明问题，揭示了HPV16 E6和C. trachomatis Pgp3蛋白通过上调Daxx表达，激活MDM2-p53通路抑制TNF-α诱导的细胞凋亡，为共感染协同致癌提供了新靶点。 宫颈癌作为全球女性第四大 ...

Genetic variations in C. trachomatis enable the pathogen to evade and survive the host immune response, compete with other bacteria or grow in a suitable environment within the host; while genetic ...

Genetic Variation in C. trachomatis. A number of chlamydial virulence factors, such as the chlamydial protease activity factor (CPAF/CT858) and the GroEL (CT110)–GroES (CT111) operon, apparently ...

Chlamydia – caused by the organism Chlamydia trachomatis – caused an estimated 128.5 million new infections in 2020, according to the World Health Organization (WHO), with a global prevalence ...

Researchers began homing in on treatments that were specific to hepatitis C itself in 2011. The results were two protease inhibitors (PIs) called boceprevir (Victrelis) and telaprevir (Incivek).

Montana Governor Greg Gianforte (R) and other business executives sat down for a discussion on the home-building industry at the Reagan National Economic Forum in Simi Valley, California. The ...

Charles C. W. Cooke is a senior editor at National Review and the host of The Charles C. W. Cooke Podcast. I don’t have questions for the thoroughly absurd Zohran Mamdani. I have questions for ...

Upon infection by an intracellular pathogen, host cells activate apoptotic pathways to limit pathogen replication. Consequently, efficient proliferation of the obligate intracellular pathogen ...

评价治疗妊娠期生殖道C.trachomatis感染的干预措施的随机对照临床试验（Randomised controlled trials, RCTs）以及以摘要形式发表的研究。整群RCT也符合纳入标准，但我们没有检索到。半随机试验和使用交叉设计的试验不符合本系统综述的纳入条件。