Transcatheter aortic valve implantation (TAVI) is now an established treatment option for elderly patients with severe ...

About this study The objective of ENVISION is to evaluate the safety and effectiveness of the Navitor Transcatheter Aortic Valve Implantation (TAVI) System for treating patients with symptomatic, ...

H uman s erum a lbumin (HSA) is the most abundant protein in plasma (~40 mg/L in blood) and a promising carrier for drug delivery since it is nontoxic, non-immunogenic, biocompatible and biodegradable ...

Mechanisms of COX Inhibition by NSAIDs All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example ...

Evidence-based recommendations on transcatheter aortic valve implantation (TAVI) for native aortic valve regurgitation. This involves implanting a replacement valve inside the faulty native valve.

The aortic valve controls the flow of blood out of the lower left chamber of the heart into the main artery (aorta). In native aortic valve regurgitation, the aortic valve cannot close properly and so ...

Conclusion & Future Perspective As the population ages and the average lifespan increases, AV disease will become increasingly prevalent, particularly in older adults. With recent advancements in ...

Objective To determine the early and long-term outcomes of conventional aortic root (ARR) and valve-sparing root replacement (VSRR) using a standard perioperative and operative approach. Methods We ...

Background The evaluation of long-term inflammatory response and function in postoperative patients with aortic valve replacement (AVR) deserves special analysis because it is important to try to ...

Introduction Bicuspid aortic valve (BAV) affects 1% of the general population. NOTCH1 was the first gene associated with BAV. The proportion of familial and sporadic BAV disease attributed to NOTCH1 ...

In the setting of aortic or mitral valve disease, left‐sided pressure overload is transmitted across the pulmonary vasculature, with pulmonary hypertension being independently associated with worse ...

The Canadian Food Inspection Agency has confirmed a case of bovine tuberculosis in a cow originating from the Pembina Valley Region of Manitoba, prompting a quarantine of the infected herd and a wider ...