February is American Heart Month, which is an appropriate time to learn how genetic testing can protect your family.

1 We now describe another family in which a similar type of neuronal migration defect has occurred in one of female identical twins with a BRCA1 gene mutation (MIM 113705). One twin developed ...

Brandi Muhle was 9 years old when her 35-year-old mother, an Omaha police officer and a marathon runner, was first diagnosed ...

Researchers determined the clinical classification of more than 90% of potential BRCA2 variants of uncertain significance in ...

Outcomes in a theoretical cohort of 10,000 patients.

In this study, non-directiveness applies to the approach of the counselling team towards family members besides the proband. When a BRCA1/2 gene mutation is found in a family, the possibility of ...

Genetics significantly impact cancer risk, particularly in inherited mutations like BRCA1/BRCA2, which increase susceptibility to breast and ovarian cancer. Expert advice suggests that understanding ...

For Evert, the diagnosis came in 2022, two years after her sister died from ovarian cancer. It turned out, she and her sister ...

5-year survival for stage III and IV (%): carriers, 38.1; noncarriers, 24.5 Median survival: p = 0.002 5-year survival for stage III and IV: p < 0.001 [46] Time of first relapse (years): BRCA ...

AstraZeneca announced that its drug Lynparza (olaparib) has been approved for use in Scotland. The approval by the Scottish ...

Prophylaxis with SERMs was estimated to prolong survival by 1.6 to 2.2 years in BRCA gene mutation carriers. [60] The ablation of the endometrial lining can be considered in BRCA mutation carriers ...