A new study shows that cells in atherosclerotic blood vessels grow in a way that resembles tumor development. This finding ...

Research has shown how cells in atherosclerosis share mutational patterns with tumor biology, with a large proportion of the ...

Atherosclerosis is a chronic cardiovascular disease that affects millions of people worldwide. The disease is marked by the accumulation of cholesterol—especially low-density lipoprotein (LDL ...

Introduction: The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate sterol metabolism and inflammation. Knockout of LXRs in macrophages greatly accelerates the ...

Atherosclerosis is a lipid-driven chronic inflammatory disease that is modulated by innate and adaptive immunity including humoral immunity. Importantly, antibody alterations achieved by genetic means ...

Researchers from the University of Southern Denmark and Odense University Hospital have studied tissue from patients with ...

Imagine a stadium packed with 75,000 fans, all wearing green and white jerseys—except one person in a solid green shirt.

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

Pervasive presence of microplastics in the environment adversely affects plants, animals, and humans. But what is ...

Authors also states that Ccr4-deficient Tregs had, as expected, impaired migration to the atherosclerotic aorta. Adoptive cell transfer of Ccr4-/- Tregs to Apoe-/- mice mimicked early atherosclerosis ...

A study led by the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) reveals the critical role of conventional type 1 dendritic cells (cDC1s) in the development of atherosclerosis ...

Discover how mRNA vaccines could revolutionize medicine by targeting 9 major diseases. Learn about breakthrough treatments ...