DOPE-PEG-Alkyne由三部分组成：炔基（Alkyne）、聚乙二醇（PEG）和二油酰基磷脂酰乙醇胺（DOPE）。这三者各自具有独特的化学性质和功能，共同构成了DOPE-PEG-Alkyne复杂而有序的分子结构。 DOPE部分：包含两个棕榈酸基团连接到甘油骨架的两个碳上，磷酸基团则连接到 ...

Dextran 是一种由葡萄糖单元组成的多糖，具有线性或分支结构。 它是一种天然存在的多糖，通常通过细菌发酵（如利用链球菌属细菌）制备。 具有良好的生物相容性、水溶性和低免疫原性。 Biotin（生物素）： 生物素是一种小分子维生素（维生素H），具有极高的 ...

1. 药物递送系统：DSPE-PEG-Alkyne 主要用于构建脂质体、纳米粒子等药物载体。炔基基团能够通过点击化学与其他功能化分子或药物结合，提升载体的靶 ...

炔基（Alkyne）： 炔基是一种高反应活性的基团，可用于与其他分子的叠氮化物（-N₃）发生点击化学反应，生成稳定的三唑环。 点击化学反应具有高 ...

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome ...

Department of Chemistry, Indian Institute of Technology Ropar, Rupnagar, Punjab 140001, India ...

Triple click chemistry has revolutionized chemical synthesis with its simplicity and efficiency, allowing for the quick and selective assembly of complex molecules. Now, in a recent study, researchers ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.orglett.4c04255. Deposition Number 2395259 contains the supplementary ...

Although these "trivalent" platforms enable the efficient synthesis of complex compounds, the selective formation of ...

Although these "trivalent" platforms enable the efficient synthesis of complex compounds, the selective formation of ...

The primary advantage of the catalyzed azide-alkyne cycloaddition over the Staudinger ligation is its faster rate. Based on preliminary studies in our laboratory, the copper-catalyzed reaction of ...