auris, as it not only is highly resistant to multiple antifungal drugs but also can withstand common hospital disinfectants. “CDC has deemed C. auris as an urgent AR [antimicrobial resistance ...

Carom seeds, commonly referred to as ajwain, belong to the Apiaceae family and are widely valued for their medicinal and nutritional properties. Also known as bishop’s weed or ajowan caraway, these ...

Antifungal agents are substances that inhibit the spread of fungi by killing fungal cells or spores or preventing their growth. Antifungal proteins (AFPs) produced by filamentous ascomycetes are ...

Aside from polyenes, there are two other main antifungal classes: azoles and echinocandins. Though it’s a polyene, mandimycin has a unique mechanism for killing fungal cells: It binds to ...

And the deadliest pathogenic fungi, such as Candida auris, are becoming increasingly resistant to approved antifungals, which is why researchers are on the hunt for new antifungal compounds.

Mandimycin is part of the family of glycosylated polyene macrolides that has provided many antifungal drugs, including AmB, nystatin and natamycin. Fungal resistance to these drugs is rare ...