Aneuploidy is frequent in cancer, but in vitro it triggers multiple cellular stresses and often delays proliferation. Through ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...

This study convincingly shows that aquaporins play a key role in blood vessel formation during zebrafish development. In particular, the paper implicates hydrostatic pressure and water flow as ...

RNA polymerase binds to a region just before the gene, called the promoter, before moving down the DNA to the gene. Enhancers are regions of DNA that act as molecular switches for turning genes on or ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...

To investigate the gene structures, conserved motifs and domains of StHAKs, detailed information on the domains of the 24 StHAK protein sequences was assayed using SMART, HMMER, and CDD database, as ...

Promoters, which start gene transcription, showed a dependence on sequence orientation but were less specific to cell types. Enhancers, which boost gene transcription, were active regardless of ...

with the first referring to the generally recognized E1 and E2 boxes and the second number representing all CANNTG sequences up to position –400 or the 5' limit of available promoter sequence.