Aging research has established that autophagy pathways become less active with age, but no one knew exactly why. The new study shows that preventing F-actin accumulation led to much more active ...

What do cells do when they are “hungry”? Eukaryotic cells cope with starving conditions by eating their own components, a process called autophagy. Aa Aa Aa Normally, when you are hungry you ...

How mitochondria drive autophagy Date: February 13, 2025 Source: Institute for Research in Biomedicine (IRB Barcelona) Summary: A new study unravels the relationship between mitofusins ...

Transient Ca 2+ fluctuations on the surface of the endoplasmic reticulum (ER) can induce liquid-liquid phase separation (LLPS) of the autophagy initiation complex FIP200, forming FIP200 puncta and ...