The eight-part gangland drama starring Sean Bean has boosted Liverpool’s economy by £9,000,000 after it received investment from Liverpool City Region’s Production Fund (LCR), its city ...

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Given below are the M.Sc. Tech(ITIMS) colleges affiliated to Dhirubhai Ambani Institute of Information and Communication Technology, Gujarat. Find all Courses and Colleges affiliated by Dhirubhai ...

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B7-H 家族成员在肿瘤微环境中的特性与作用 B7-H2（ICOSL） 分子特征与表达谱：ICOSL 的分子结构包含细胞外 N 端免疫球蛋白（Ig）可变（V 型）结构域、Ig 恒定（C 型）结构域、跨膜结构域和胞内结构域，缺乏经典的免疫受体酪氨酸抑制基序（ITIMs）或激活基序（ITAMs ...

在讨论部分，研究人员指出，本研究揭示了 SIRPα 在 SAH 后调控吞噬作用和神经炎症的重要机制。SAH 后，SIRPα 的免疫受体酪氨酸抑制基序（ITIMs）磷酸化，招募并磷酸化 SHP1 和 SHP2，其中 SHP1 发挥关键作用。磷酸化的 SHP1 使 p-STAT6 去磷酸化，阻止其进入细胞核 ...