Escherichia coli dihydrofolate reductase (DHFR) has several flexible loops surrounding the active site that play a functional role in substrate and cofactor binding and in catalysis. We have used ...

Copper nitrite reductase contains a T1 and T2 Cu center and catalyzes the one electron reduction of nitrite to NO. This study determines that reaction of the reduced enzyme with excess NO generates ...

作为葡萄糖代谢分支多元醇通路的限速酶，Aldo-keto reductase 1B（AKR1B）亚家族最初因与糖尿病慢性并发症（如视网膜病变、神经病变、肾病变和白内障 ...

Androgenetic alopecia is the most common form of non-cicatricial hair loss, affecting a significant proportion of the population, particularly men. Due to increasing societal demands for a flawless ...

Algerian boxer Imane Khelif, gold medalist at the 2024 Olympics, faces controversy over a leaked medical report suggesting she has 5-alpha reductase deficiency | World News ...

Rogaine (minoxidil) and Propecia (finasteride) are potential treatment options for hair loss. While they serve similar purposes, they belong to separate drug classes and work in different ways.

Studies have shown that the activity of 5A-reductase type II in hair follicles in alopecia AGA region is significantly higher than that in non-alopecia region, and the 5 α -reductase in the tissue can ...

Keywords: CyHV-2, ORF23, ORF141, ribonucleotide reductase, hydroxyurea Citation: Cheng W, Chen Q, Ren Y, Zhang Y, Lu L, Gui L and Xu D (2023) The identification of viral ribonucleotide reductase ...

The Google Pixel 5a packs a serious punch, even after Google has unveiled its new Pixel 6 handsets. This is the phone to get if you want the best photography experience under $500.

1. Pixel 6a 2. Pixel 5a The Google Pixel 5a came at the end of a design drought for Google, and it’s fair to say the design isn’t exciting. If you’re being nice, you can call it “safe”.

Using a high-throughput screening approach, we showed that mutations in Aα results in synthetic lethality following treatment with inhibitors of ribonucleotide reductase (RNR). In vivo, multiple ...

1 Department of Breast and Thyroid Surgery, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China 2 Center for Novel Target and Therapeutic Intervention, Institute of Life ...