Endothelin-1 is a small vasoconstrictor peptide that was first identified in 1988. Here we review the evidence implicating ET-1 in tumorigenesis. In particular, we concentrate on the role of ET-1 ...

Biolexis Therapeutics’ small molecule BLX-7006 reduced the weight of obese mice by 15% over a 28-day span. | Another contender has emerged in the race to develop oral GLP-1 drugs for weight loss.

Inipharm Initiates Dosing in Phase 1 Study of Its Small Molecule Inhibitor of HSD17B13. November 30, 2023 08:00 AM Eastern Standard Time. BELLEVUE, Wash. & SAN DIEGO-- ...

A small molecule may be an effective alternative to anti-PD1/PD-L1 immunotherapy antibodies used to treat all types of cancer. About Careers Internship MedBlog Contact us English (US) ...

Septerna is developing SEP-786, a novel, potent and selective oral small molecule parathyroid hormone 1 receptor (PTH1R) agonist for the treatment of patients with hypoparathyroidism, a rare ...

Roche reported its oral GLP-1 agonist led to an average 6.1% weight loss at four weeks, according to preliminary results from part of a Phase 1 study. The small molecule comes from Roche’s $2.7 ...