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We have studied the conformational dynamics associated with the nanoscale DNA bending induced by human immunodeficiency virus type 1 (HIV-1) nucleocapsid (NC) protein using single-molecule Förster ...

Abstract—The antiatherogenic effect of estrogen is mediated, in part, by inhibitory effects on endothelial vascular cell adhesion molecule-1 (VCAM-1) expression.To determine the mechanism by which ...

Abstract. 5-Hydroxymethylfurfural (HMF) is a key renewable platform compound for production of fuels and chemical intermediates. The production of 5-hydroxymethylfurfural (HMF) from fructose ...

Standard has awarded Molecule.one $1 million in recognition of its state-of-the-art AI platform that will accelerate the development and production of pharmaceuticals from cardiovascular and ...

We investigated the single 1,4-benzenediamine molecule bridging between Au or Pt electrodes. The conductances of the molecular junctions with the Au−NH2 and Pt−NH2 bonds (Au−NH2 and Pt−NH2 molecular ...

The Phase 1/1b trial, NCT06253871, is an open-label, multi-center, dose escalation and dose optimization study, designed to evaluate tolerability, pharmacokinetics, pharmacodynamics, and preliminary ...