BIIB080 is an antisense oligonucleotide therapy designed to target microtubule-associated protein tau mRNA and reduce the production of tau.

Abnormal accumulation of tau protein in the brain has been associated ... Findings showed BIIB080 dose-dependently reduced soluble tau biomarkers in cerebrospinal fluid (t-tau and p-tau181 ...

Researchers have developed a blood test based on a protein biomarker for tau tangles that can help diagnose Alzheimer’s ...

Alzheimer’s blood tests may one day allow patients and their doctors to track their individual progress in reducing risk, ...

In recent years, scientists have worked hard to find better ways to detect dementia, including Alzheimer's disease, long ...

Worley was part of a team that showed how the loss of one of the two proteins used in the test disrupts synapses and leads to ...

Previously, the WashU researchers had linked the level of a protein known as MTBR-tau243 in cerebrospinal fluid as a valid proxy for levels of tau tangles ... both of these biomarkers are positive ...

Dementia affects millions of people worldwide, causing a serious impact on the economy and the healthcare system. Alzheimer’s ...