EMBO Press publishes five scientific journals: The EMBO Journal - Submit here The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology ...

Selenoprotein T (SELENOT), a selenocysteine (Sec)-containing and evolutionarily conserved protein, is anchored to the endoplasmic reticulum (ER) membrane through a hydrophobic domain (Gladyshev et al, ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

Physiological regulation of transgene expression is a major challenge in gene therapy. Onasemnogene abeparvovec (Zolgensma ®) is an approved adeno-associated virus (AAV) vector gene therapy for ...

ITM2B/BRI2 mutations cause Alzheimer’s Disease (AD)-related dementias. We observe heightened ITM2B/BRI2 expression in microglia, a pivotal cell type in AD due to risk-increasing variants in the ...

Motile cells can use and switch between different modes of migration. Here, we use traction force microscopy and fluorescent labeling of actin and myosin to quantify and correlate traction force ...

Neurodegenerative diseases are prevalent age-related diseases, with Alzheimer’s disease (AD) as a prototype of such conditions. As of 2024, approximately 6.9 million Americans are affected by AD, ...

Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

In this work, we used top‐down system biology approach with causal inference analysis to reconstruct a multi‐omic network (transcriptome, metabolome, lipidome, single cell RNA sequencing) and to ...

Recently, we were able to show that both SARS-CoV-2 infection and mRNA vaccination prime human monocyte-derived macrophages for potent secretion of pro-inflammatory cytokines following restimulation ...

Our study identified two fibrillarin homologs in planarian Schmidtea mediterranea, Smed-fbl-1 (fbl-1) and Smed-fbl-2 (fbl-2).We found that fbl-1 and fbl-2 are differentially expressed in neoblasts and ...