5 Laboratory of Immunology, Faculty of Medicine, Vandoeuvre lès Nancy, France 6 Laboratory of Biochemistry, INSERM U724, Faculty of Medicine, Vandoeuvre lès Nancy, France Background: Homocysteine may ...

Department of Clinical Neurosciences, University of Cambridge Clinical School, Addenbrooke’s Hospital, Cambridge CB2 0QQ, UK N Robertson, Helen Durham Neuro-inflammatory Centre, Department of ...

Drugs used for therapeutic interventions either alone or in combination may sometimes cause unexpected toxicity to the muscles, resulting in a varying degree of symptomatology, from mild discomfort ...

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting the upper and lower motor neurons. A key clinical feature of ALS is the absence of accurate, early-stage ...

We analysed clinical trials of pharmacological interventions on patients with amyotrophic lateral sclerosis (ALS), and compared study quality and design features. The systematic review included ...

Correspondence to Dr Joseph Jankovic, Department of Neurology, Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine, 6550 Fannin, Suite 1801, Houston, TX 77030, USA; ...

The Grey Walter Department of Clinical Neurophysiology, Frenchay Hospital, Bristol, UK Correspondence to: Dr Nick Kane The Grey Walter Department of Clinical Neurophysiology, Frenchay Hospital, ...

Department of Neurology, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland Correspondence to Dr Tuula Pirttilä, Department of Neurology, Bldg 5, Kuopio University Hospital POB ...

Background Corticospinal tract (CST) degeneration and cortical atrophy are consistent features of amyotrophic lateral sclerosis (ALS). We hypothesised that neurite orientation dispersion and density ...

Objective To evaluate the efficacy and safety of intramuscular ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis (ALS). Methods 373 patients with ALS (El Escorial definite ...

Adult-onset leukodystrophies and genetic leukoencephalopathies comprise a diverse group of neurodegenerative disorders of white matter with a wide age of onset and phenotypic spectrum. Patients with ...