Healthcare delivery is being transformed by the rapid growth of data, advancements in artificial intelligence (AI) and other ...

Journal clubs, typically involving a group of health professionals or trainees who discuss recent study findings, have long ...

What it is Overdetection refers to the identification of abnormalities that were never going to cause harm, abnormalities that do not progress, that progress too slowly to cause symptoms or harm ...

A systematic review identifies, appraises and synthesises all the empirical evidence from studies that meet prespecified eligibility criteria to answer a specific research question. As part of the ...

Introduction The concepts of evidence-based medicine are evolving as limitations of early models are addressed. In this editorial, we present a new model for evidence-based clinical decision making ...

Registration of health and medical research is an effective way of improving the transparency and credibility of evidence. Registration involves pre-specifying the research objectives, design, methods ...

Understanding the causes of deaths and how they can be prevented is critical for improving healthcare outcomes. At a population level, over-reporting or under-reporting of deaths can have a profound ...

Objectives Over the last two decades, the incidence of endometrial cancer has risen by 55% whilst its mortality has been stable.1 These trends have raised concerns that the increase in the incidence ...

The effects of statins in the elderly are better informed by absolute effects and the number needed to evaluate the benefit to harm balance. Such an approach enables patients to make more informative ...

Objective The objectives of this scoping review were to provide an overview of existing guidelines for the development and validation of patient-reported outcome measures (PROMs), review them for ...

In addition to reducing patient harms and wasted resources, efforts to reduce low-value care produce significant climate and population health benefits, but these benefits are typically not elucidated ...